Disease Eradication through Thermostable PPR Vaccines

Reliable, Effective, and Accessible Disease Control for Small Ruminants.

The vaccine is a homologous live attenuated solution that effectively guards small ruminants against PPR. It comes in two variants: the ILRI thermotolerant PPR vaccine produced through the Thermovac process, and Xerovac, an established option. Both are proven to remain stable at ambient temperatures for extended periods, even withstanding spikes of 40°C.

This technology is TAAT1 validated.

8•7

Scaling readiness: idea maturity 8/9; level of use 7/9

Cost: $$$ 0.5—1.0 USD

Vaccine dose cost per animal

ROI: $$$

IP

Open source / open access

Problem

High Mortality Rates: PPR is a fast-spreading viral disease with high mortality rates, especially among younger animals.
Limited Vaccine Storage: The requirement for cold storage has limited the widespread use of the vaccine within eradication programs.
Economic Losses: Economic losses from PPR across Africa and Asia are estimated to be US $2.1 billion per year.
Vaccine Stability: Previous constraints included maintaining vaccine stability, especially in areas with limited access to cold storage.
Limited Coverage: The need for cold storage restricted the coverage of vaccination campaigns, limiting the protection of animals.
Outbreak Reporting: PPR is a notifiable disease, necessitating the reporting of outbreaks to national veterinary authorities.
Disease Surveillance: Disease surveillance, including animal movement monitoring and quarantine measures, is crucial for controlling outbreaks and preventing spread.
Biosecurity Measures: Identification of high-risk areas with inadequate biosecurity measures is essential to prevent infection and spread.

Solution

Stability at Ambient Temperatures: Eliminates the need for cold storage, making the vaccine widely accessible and reducing logistical challenges.
Extended Shelf Life: Remains effective for up to two weeks at ambient temperatures, ensuring vaccines remain potent even in areas with limited refrigeration facilities.
Proven Effectiveness: Demonstrated efficacy in several countries, providing reliable protection against PPR in small ruminants.
Cost-Effective: Reduces storage costs associated with cold chain maintenance, making the vaccine a more affordable solution for farmers.
Improved Coverage: Enables vaccination of a larger number of animals in less time, contributing to more comprehensive disease control efforts.
Lifetime Immunity for Most Animals: Offers long-term protection, reducing mortality rates and economic losses associated with PPR outbreaks.
Compliance with Eradication Efforts: Aligns with international standards set by organizations like the World Organization for Animal Health and the Food and Agriculture Organization, supporting global efforts to eradicate PPR.

Key points to design your business plan

Using Disease Eradication through Thermostable PPR Vaccines technology significantly reduces the incidence of PPR outbreaks among small ruminants, thereby enhancing food security and improving livelihoods for farmers.

As essential collaborators, sellers of the product are indispensable. Regarding cost considerations, the vaccine dose typically ranges from 0.5 to 1.0 USD per animal, with a mere investment of USD 300 enough to empower a local animal health technician to establish a profitable vaccination enterprise.

Vaccination is recommended for all goats and sheep, irrespective of their production scale. A well-organized vaccinator can administer treatment to up to 5,000 animals monthly, ensuring a business with a satisfactory return on investment.

Animal owners are not obligated to obtain permits but are strongly encouraged or required to ensure all their animals receive treatment.

Adults 18 and over: Positive high

Others: No impact

The poor: Positive low

Under 18: Positive low

Women: Positive medium

Climate adaptability: Highly adaptable

Farmer climate change readiness: Significant improvement

Biodiversity: Positive impact on biodiversity

Environmental health: Moderately improves environmental health

Water use: Same amount of water used

Countries with a green colour: Tested & adopted
Countries with a bright green colour: Adopted
Countries with a yellow colour: Tested

Countries where the technology has been tested and adopted
Country	Tested	Adopted
Burkina Faso	Tested	Adopted
Cameroon	Tested	Adopted
Kenya	Tested	Adopted
Niger	Tested	Adopted
Nigeria	Tested	Adopted
Somalia	Tested	Adopted
South Sudan	Tested	Adopted
Tanzania	Tested	Adopted
Uganda	Tested	Adopted

This technology can be used in the colored agro-ecological zones. Any zones shown in white are not suitable for this technology.

Agro-ecological zones where this technology can be used
AEZ	Subtropic - warm	Subtropic - cool	Tropic - warm	Tropic - cool
Arid
Semiarid
Subhumid
Humid

Source: HarvestChoice/IFPRI 2009

The United Nations Sustainable Development Goals that are applicable to this technology.

Goal 1: no poverty

Goal 2: zero hunger

Goal 3: good health and well-being

Goal 8: decent work and economic growth

Goal 9: industry, innovation and infrastructure

Goal 12: responsible production and consumption

Goal 13: climate action

Report outbreaks to national veterinary authorities as PPR is a notifiable disease.
Implement disease surveillance considering animal movement, farm quarantine, and identification of high-risk areas.
Source vaccines from reliable suppliers and ensure proper cold chain management.
Administer vaccines through trained and certified vaccinators, ensuring correct dosage.
Monitor vaccinated animals for signs of immunity and address any concerns promptly.

Last updated on 28 August 2024