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PPR Vaccines Disease Eradication through Thermostable PPR Vaccines

Reliable, Effective, and Accessible Disease Control for Small Ruminants.

The vaccine is a homologous live attenuated solution that effectively guards small ruminants against PPR. It comes in two variants: the ILRI thermotolerant PPR vaccine produced through the Thermovac process, and Xerovac, an established option. Both are proven to remain stable at ambient temperatures for extended periods, even withstanding spikes of 40°C.


This technology is TAAT1 validated.


Scaling readiness: idea maturity 8/9; level of use 7/9

Cost: $$$ 0.5—1.0 USD

Vaccine dose cost per animal

ROI: $$$


Open source / open access


  • High Mortality Rates: PPR is a fast-spreading viral disease with high mortality rates, especially among younger animals.
  • Limited Vaccine Storage: The requirement for cold storage has limited the widespread use of the vaccine within eradication programs.
  • Economic Losses: Economic losses from PPR across Africa and Asia are estimated to be US $2.1 billion per year.
  • Vaccine Stability: Previous constraints included maintaining vaccine stability, especially in areas with limited access to cold storage.
  • Limited Coverage: The need for cold storage restricted the coverage of vaccination campaigns, limiting the protection of animals.
  • Outbreak Reporting: PPR is a notifiable disease, necessitating the reporting of outbreaks to national veterinary authorities.
  • Disease Surveillance: Disease surveillance, including animal movement monitoring and quarantine measures, is crucial for controlling outbreaks and preventing spread.
  • Biosecurity Measures: Identification of high-risk areas with inadequate biosecurity measures is essential to prevent infection and spread.


  • Stability at Ambient Temperatures: Eliminates the need for cold storage, making the vaccine widely accessible and reducing logistical challenges.
  • Extended Shelf Life: Remains effective for up to two weeks at ambient temperatures, ensuring vaccines remain potent even in areas with limited refrigeration facilities.
  • Proven Effectiveness: Demonstrated efficacy in several countries, providing reliable protection against PPR in small ruminants.
  • Cost-Effective: Reduces storage costs associated with cold chain maintenance, making the vaccine a more affordable solution for farmers.
  • Improved Coverage: Enables vaccination of a larger number of animals in less time, contributing to more comprehensive disease control efforts.
  • Lifetime Immunity for Most Animals: Offers long-term protection, reducing mortality rates and economic losses associated with PPR outbreaks.
  • Compliance with Eradication Efforts: Aligns with international standards set by organizations like the World Organization for Animal Health and the Food and Agriculture Organization, supporting global efforts to eradicate PPR.

Key points to design your business plan

Using Disease Eradication through Thermostable PPR Vaccines technology significantly reduces the incidence of PPR outbreaks among small ruminants, thereby enhancing food security and improving livelihoods for farmers.

As essential collaborators, sellers of the product are indispensable. Regarding cost considerations, the vaccine dose typically ranges from 0.5 to 1.0 USD per animal, with a mere investment of USD 300 enough to empower a local animal health technician to establish a profitable vaccination enterprise.

Vaccination is recommended for all goats and sheep, irrespective of their production scale. A well-organized vaccinator can administer treatment to up to 5,000 animals monthly, ensuring a business with a satisfactory return on investment.

Animal owners are not obligated to obtain permits but are strongly encouraged or required to ensure all their animals receive treatment.


Positive or neutral impact

Adults 18 and over
Positive high
No impact
The poor
Positive low
Under 18
Positive low
Positive medium

Positive or neutral impact

Climate adaptability
It adapts really well
Adaptability for farmers
It helps a lot
It helps them grow and thrive
It makes a little difference
Water usage
It uses the same amount of water

Countries with a green colour
Tested & adopted
Countries with a bright green colour
Countries with a yellow colour
Egypt Equatorial Guinea Ethiopia Algeria Angola Benin Botswana Burundi Burkina Faso Democratic Republic of the Congo Djibouti Côte d’Ivoire Eritrea Gabon Gambia Ghana Guinea Guinea-Bissau Cameroon Kenya Libya Liberia Madagascar Mali Malawi Morocco Mauritania Mozambique Namibia Niger Nigeria Republic of the Congo Rwanda Zambia Senegal Sierra Leone Zimbabwe Somalia South Sudan Sudan South Africa Eswatini Tanzania Togo Tunisia Chad Uganda Western Sahara Central African Republic Lesotho
Countries where the technology has been tested and adopted
Country Tested Adopted
Burkina Faso Tested Adopted
Cameroon Tested Adopted
Kenya Tested Adopted
Niger Tested Adopted
Nigeria Tested Adopted
Somalia Tested Adopted
South Sudan Tested Adopted
Tanzania Tested Adopted
Uganda Tested Adopted

This technology can be used in the colored agro-ecological zones. Any zones shown in white are not suitable for this technology.

Agro-ecological zones where this technology can be used
AEZ Subtropic - warm Subtropic - cool Tropic - warm Tropic - cool

Source: HarvestChoice/IFPRI 2009

The United Nations Sustainable Development Goals that are applicable to this technology.

Sustainable Development Goal 1: no poverty
Goal 1: no poverty
Sustainable Development Goal 2: zero hunger
Goal 2: zero hunger
Sustainable Development Goal 3: good health and well-being
Goal 3: good health and well-being
Sustainable Development Goal 8: decent work and economic growth
Goal 8: decent work and economic growth
Sustainable Development Goal 9: industry, innovation and infrastructure
Goal 9: industry, innovation and infrastructure
Sustainable Development Goal 12: responsible production and consumption
Goal 12: responsible production and consumption
Sustainable Development Goal 13: climate action
Goal 13: climate action

  1. Report outbreaks to national veterinary authorities as PPR is a notifiable disease.
  2. Implement disease surveillance considering animal movement, farm quarantine, and identification of high-risk areas.
  3. Source vaccines from reliable suppliers and ensure proper cold chain management.
  4. Administer vaccines through trained and certified vaccinators, ensuring correct dosage.
  5. Monitor vaccinated animals for signs of immunity and address any concerns promptly.

Last updated on 22 May 2024